Rare functioning pancreatic endocrine tumors.

نویسندگان

  • Dermot O'Toole
  • Ramon Salazar
  • Massimo Falconi
  • Gregory Kaltsas
  • Anne Couvelard
  • Wouter W de Herder
  • Rudolf Hyrdel
  • George Nikou
  • Eric Krenning
  • Marie-Pierre Vullierme
  • Martin Caplin
  • Robert Jensen
  • Barbro Eriksson
چکیده

a Department of Gastroenterology, Beaujon Hospital, Clichy , France; b Department of Oncology, Institut Català d’Oncologia, Barcelona , Spain; c Department of Surgery, Verona University, Verona , Italy; d Department of Endocrinology and Metabolism, Genimatas Hospital, Athens , Greece; e Department of Gastroenterology, Beaujon Hospital, Clichy , France; f Department of Endocrinology, Erasmus MC University, Rotterdam , The Netherlands; g Department of Internal Medicine, Martin University, Martin , Slovakia; h Department of Propaedeutic Internal Medicine, Laiko Hospital, Athens , Greece; i Department of Nuclear Medicine, Erasmus MC University, Rotterdam , The Netherlands; j Department of Gastroenterology, Beaujon Hospital, Clichy , France; k Department of Gastroenterology, Royal Free Hospital, London , UK; l Department of Cell Biology, National Institute of Health, Bethesda, Md. , USA; m Department of Endocrinology, University Hospital, Uppsala , Sweden

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Surgical strategy in the treatment of pancreatic neuroendocrine tumors.

Endocrine pancreatic tumors are rare and their surgical treatment is often debated. This review analyzes the management and the different indications in functioning and non-functioning neoplasms. The choice among different procedures is described as well as the role of intra operative ultrasound. Moreover, the different patterns of tumor spread are considered (local, loco-regional and metastati...

متن کامل

معرفی یک مورد انسولینوما در زمینه سندرم نئوپلازی اندوکرینی متعدد نوعI

Introduction: The pancreatic endocrine tumors are rare. Insulinoma is the most common pancreatic endocrine neoplasm.30% of pancreatic tumors in MEN type I are beta cell tumors. Case Report: The presented case is a 23 year old male with a family history of MEN I syndrome .The patient presented with whipple triad. Radiologic studies revealed two small and round masses in body and tail of pan...

متن کامل

New Genetics and Genomic Data on Pancreatic Neuroendocrine Tumors: Implications for Diagnosis, Treatment, and Targeted Therapies.

The recent findings on the roles of death-associated protein 6/α-thalassemia/mental retardation X-linked (DAXX/ATRX) in the development of pancreatic neuroendocrine tumors (PanNETs) have led to major advances in the molecular understanding of these rare tumors and open up completely new therapeutic windows. This overview aims at giving a simplified view on these findings and their possible ther...

متن کامل

Pancreatic endocrine tumors with intraductal growth into the main pancreatic duct and tumor thrombus within the portal vein: a case report and review of the literature.

Pancreatic endocrine tumors are rare tumors classified into "functioning" and "nonfunctioning" tumors. A 68-year-old man was admitted to our hospital with the chief compliant of abdominal pain. Various imaging studies demonstrated a mass in the head of the pancreas with intraductal growth into the main pancreatic duct and an intraportal mass. The patient underwent a curative surgical operation....

متن کامل

Pancreatic Neuroendocrine Tumor with Atypical Radiologic Presentation

An atypical radiographic presentation of a rare non-functional pancreatic neuroendocrine tumor as seen on US, CT and MRI is described. Radiographic-pathologic correlation via gross autopsy specimens and immuno-histochemical staining demonstrates the pancreas to be markedly enlarged with extensive calcifications and numerous tiny cysts secondary to diffuse neoplastic infiltration without a focal...

متن کامل

Genetic Alterations in Gastrinomas and Nonfunctioning Pancreatic Neuroendocrine Tumors: An Analysis ofpl6/MTS1 Tumor Suppressor Gene Inactivation'

Neoplasms of the endocrine pancreas are extremely rare, and molecu lar mechanisms influencing their development are poorly understood. Nevertheless, gastrinomas have become a paradigm for the study of hormonafly active tumors In the present study, 12 gastrinoma and non functioning pancreatic neuroendocrine tumor specimens were evaluated for genetic alterations of the pl6IMTSl tumor suppressor g...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Neuroendocrinology

دوره 84 3  شماره 

صفحات  -

تاریخ انتشار 2006